Melanotan I (MT1) Peptide
Out of Stock- CAS
- 75921-69-6
- Molecular weight
- 1646.85 g/mol
- Purity (HPLC)
- COA pending
- Lot / COA
- Pending
Out of stock
- Free shippingOn every order
- Free 2nd Day AirOn orders $200+
Research Use Only
All products are intended solely for laboratory research and are not for human or animal consumption. By purchasing, the buyer agrees to use these products in compliance with all applicable laws.
Specifications
- CAS
- 75921-69-6
- Molecular formula
- C78H111N21O19
- Molecular weight
- 1646.85 g/mol
- Purity (HPLC)
- COA pending
- Lot / COA
- Pending
- PubChem CID
- 16197727
Melanotan I (MT1) Peptide Overview
Melanotan I — also written Melanotan 1, and referred to in research shorthand as the MT1 or MT-1 peptide — is a synthetic tridecapeptide composed of 13 amino acids. It was originally derived from the naturally occurring hormone alpha-melanocyte-stimulating hormone (α-MSH), modified at two positions to resist enzymatic breakdown. Since its characterization in the early 1980s, Melanotan I has been studied extensively in controlled experimental settings for its potential influence on melanocyte activity, receptor signaling, and pigmentary processes.
Melanotan II and PT-141 are related melanocortin-receptor research peptides in the Medicina Labs catalog.
History
The peptide was first synthesized by researchers at the University of Arizona investigating more stable analogs of α-MSH, which degrades within minutes in circulation. Early experiments focused on its ability to sustain melanocyte stimulation and prolonged biological activity in pigmentation models. Over time, studies broadened into receptor, photobiology, and systemic systems, where Melanotan I has been used to examine melanogenesis and melanocortin 1 receptor (MC1R) pharmacology.
Melanotan I Structure
CAS #: 75921-69-6
Molecular Formula: C78H111N21O19
Molecular Weight: 1646.85 g/mol
PubChem ID: 16197727
Research Findings
Melanotan I has been studied in pigmentary, receptor, photobiology, and systemic models, with reports of activity in melanin synthesis, melanocortin-receptor binding, UV-response modulation, and cellular signaling. Research has also examined cAMP-mediated signaling downstream of MC1R activation in preclinical systems.
Key Areas of Research:
- Pigmentary: Melanogenesis, eumelanin, melanocytes
- Receptor: MC1R binding, melanocortin signaling, selectivity
- Photobiology: UV response, phototoxicity models, skin
- Systemic: Signaling, receptor distribution, pathway dynamics
Together, these findings suggest broad experimental utility for Melanotan I across multiple biological pathways. Its activity in pigmentary, receptor, photobiology, and systemic models provides a foundation for exploring diverse aspects of molecular biology. By influencing processes such as melanin regulation, receptor activation, and molecular signaling, Melanotan I offers a versatile platform for research into pathway dynamics and melanocortin receptor signaling within experimental settings.
Langendonk J.G. et al., New England Journal of Medicine, 2015
Our Process
Precision Lyophilization
Each batch is freeze-dried and sealed for stability until reconstitution.
Verified Purity
Every batch is third-party tested with HPLC and mass spectrometry.
Careful Fulfillment
Orders ship within 24 hours from our U.S. facility.
