GHK-Cu Peptide
In Stock- CAS
- 89030-95-5
- Molecular weight
- 402.92 g/mol
- Purity (HPLC)
- COA pending
- Lot / COA
- Pending
- Free shippingOn every order
- Free 2nd Day AirOn orders $200+
Research Use Only
All products are intended solely for laboratory research and are not for human or animal consumption. By purchasing, the buyer agrees to use these products in compliance with all applicable laws.
Specifications
- CAS
- 89030-95-5
- Molecular formula
- C14H23CuN6O4+
- Molecular weight
- 402.92 g/mol
- Purity (HPLC)
- COA pending
- Lot / COA
- Pending
- PubChem CID
- 71587328
GHK-Cu Peptide Overview
The GHK-Cu peptide (glycyl-L-histidyl-L-lysine:copper(II)) is a naturally occurring copper-binding tripeptide studied for its role in molecular signaling, matrix remodeling, and pathway dynamics. In laboratory and preclinical models, GHK-Cu has been associated with modulation of gene expression, angiogenesis, and extracellular matrix activity, making it a valuable tool for research into experimental biology.
GHK-Cu is also supplied as one constituent of two multi-compound Medicina Labs research formulations, GLOW and KLOW.
For the chemistry distinction between the free tripeptide and the copper complex, see GHK vs GHK-Cu.
History
GHK was first identified in the 1970s in biological plasma samples, where it was characterized as a tripeptide with high affinity for copper(II) ions. Subsequent research demonstrated that complexing GHK with copper enhanced its biological activity, particularly in processes related to extracellular matrix dynamics and molecular remodeling. Over the years, GHK-Cu has been extensively studied in models of epithelial biology, angiogenesis, and systemic regulation of gene expression.
GHK-Cu Structure
CAS #: 89030-95-5
Molecular Formula: C14H23CuN6O4+
Molecular Weight: 402.92 g/mol
PubChem ID: 71587328
In the copper complex, the Cu(II) ion is coordinated by the N-terminal amino nitrogen of glycine, the deprotonated amide nitrogen of the glycine–histidine peptide bond, and an imidazole nitrogen of histidine.
Research Findings
GHK-Cu has been studied in structural, epithelial, and systemic models, with research highlighting its effects on collagen synthesis, extracellular matrix dynamics, and molecular remodeling. Studies also note its role in epithelial modeling, follicle signaling, and cytokine modulation in preclinical settings.
Key Areas of Research:
- Structural: Collagen, matrix, connective signaling
- Epithelial: Matrix dynamics, remodeling, follicle signaling
- Systemic: Cytokine modulation, viability, pathway dynamics
Together, these findings suggest broad experimental potential for GHK-Cu across structural, epithelial, and systemic pathways. By engaging collagen-synthesis pathways, gene-expression regulation, and cytokine signaling, GHK-Cu provides a versatile platform for research into matrix dynamics, epithelial biology, and copper-peptide coordination chemistry in laboratory settings.
Our Process
Precision Lyophilization
Each batch is freeze-dried and sealed for stability until reconstitution.
Verified Purity
Every batch is third-party tested with HPLC and mass spectrometry.
Careful Fulfillment
Orders ship within 24 hours from our U.S. facility.
