Melanotan II (MT2) Peptide
Out of Stock- CAS
- 121062-08-6
- Molecular weight
- 1024.18 g/mol
- Purity (HPLC)
- COA pending
- Lot / COA
- Pending
Out of stock
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Research Use Only
All products are intended solely for laboratory research and are not for human or animal consumption. By purchasing, the buyer agrees to use these products in compliance with all applicable laws.
Specifications
- CAS
- 121062-08-6
- Molecular formula
- C50H69N15O9
- Molecular weight
- 1024.18 g/mol
- Purity (HPLC)
- COA pending
- Lot / COA
- Pending
- PubChem CID
- 92432
Melanotan II (MT2) Overview
Melanotan II, often referred to as the MT2 peptide (also written Melanotan 2 or MT-2), is a synthetic cyclic heptapeptide analog of α-MSH, a naturally occurring peptide that regulates pigmentation through target receptor activation. Originally developed as a research compound for studying melanogenesis and UV-response pathways, MT-II exhibits high affinity for its primary target receptor subtypes. Through selective binding to multiple pathway targets, it has been examined in research contexts involving pigmentation pathways, endocrine signaling, and peptide-receptor pharmacology in laboratory settings.
Melanotan I and PT-141 are related melanocortin-receptor research peptides in the Medicina Labs catalog.
History
Melanotan II was synthesized in the 1990s at the University of Arizona as part of peptide signaling research aimed at developing stable melanocortin-receptor research compounds. Building upon earlier work with linear melanotropic peptides, researchers created this cyclized analog to improve stability and target selectivity. The peptide emerged from systematic structure-activity relationship studies examining peptide-receptor agonist dynamics.
Melanotan II Structure
CAS #: 121062-08-6
Molecular Formula: C50H69N15O9
Molecular Weight: 1024.18 g/mol
PubChem ID: 92432
Research Findings
Melanotan II has been investigated in peptide-receptor research and pigmentation pathway studies, with particular focus on target selectivity, signaling cascades, and downstream biological responses in controlled experimental settings. Research has explored its interactions with multiple target receptor subtypes and associated molecular mechanisms.
Key Areas of Research:
- Receptor: Target binding, activation, selectivity
- Pigmentation: Melanogenesis, tyrosinase, eumelanin
- Pharmacology: Structure-activity, ligand dynamics
- Signaling: cAMP pathways, MITF, downstream cascades
Together, these investigations provide insight into peptide-receptor biology and pigmentation pathway regulation. Through its multi-target activity, MT-II serves as a research tool for examining signaling systems, receptor-ligand interactions, and downstream molecular responses in experimental pigmentation and receptor expression models.
Our Process
Precision Lyophilization
Each batch is freeze-dried and sealed for stability until reconstitution.
Verified Purity
Every batch is third-party tested with HPLC and mass spectrometry.
Careful Fulfillment
Orders ship within 24 hours from our U.S. facility.
