LP1-S Peptide
Out of Stock- CAS
- 910463-68-2
- Molecular weight
- ~4114 g/mol
- Form
- Lyophilized powder
- Purity (HPLC)
- COA pending
- Storage
- −20 °C or colder
- Lot / COA
- Pending
- Free shippingOn every order
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Research Use Only
All products are intended solely for laboratory research and are not for human or animal consumption. By purchasing, the buyer agrees to use these products in compliance with all applicable laws.
Specifications
- CAS
- 910463-68-2
- Molecular formula
- C187H291N45O59
- Molecular weight
- ~4114 g/mol
- Form
- Lyophilized powder
- Purity (HPLC)
- COA pending
- Storage
- −20 °C or colder
- Lot / COA
- Pending
- PubChem CID
- 56843331
LP1-S Peptide Overview
LP1-S is a synthetic peptide analog designed for selective activity at the glucagon-like peptide-1 receptor (GLP-1R). Structural modifications to the native GLP-1 framework increase resistance to enzymatic degradation and extend receptor activity, making the compound useful in experimental models examining endocrine signaling and metabolic pathway regulation. LP1-S is the Medicina Labs catalog designation for this material; its identity is defined by the CAS registry number, molecular formula, and PubChem identifier listed in the structure section below.
Research involving LP1-S has examined receptor activation, intracellular signaling cascades, glucose-associated regulatory pathways, lipid signaling, and central endocrine mechanisms.
Related receptor-signaling research materials in the Medicina Labs catalog include LP3-R and Cagrilintide.
History
LP1-S emerged from decades of research into GLP-1 biology and the development of more stable analogs of endogenous GLP-1. Native GLP-1 is rapidly degraded, creating interest in modified peptides capable of maintaining receptor activity for substantially longer periods.
Medicinal chemistry research ultimately produced a modified GLP-1 analog incorporating amino-acid substitutions and fatty-acid conjugation to increase molecular stability and albumin association. The compound's development was described in detail by Lau and colleagues in 2015.
LP1-S Structure
CAS #: 910463-68-2
Molecular Formula: C187H291N45O59
Molecular Weight: ~4114 g/mol
PubChem ID: 56843331
Research Findings
LP1-S has been examined across receptor, endocrine, cellular, and systemic experimental models. Research has focused on GLP-1 receptor activity and the intracellular pathways activated following receptor engagement.
Key Areas of Research:
- Receptor: GLP-1R binding and activation
- Endocrine: Glucose-associated signaling pathways
- Molecular: cAMP-mediated signaling and downstream cascades
- Systemic: Metabolic, lipid, and energy-regulation pathways
Together, these findings provide a framework for investigating selective GLP-1 receptor biology and the downstream molecular processes that follow sustained receptor activation.
Specifications, Testing & Storage
LP1-S is supplied in 5mg, 10mg, 15mg, and 30mg sizes as lyophilized (freeze-dried) powder in sealed glass vials, each labeled with the product name, lot number, quantity, and storage instructions.
Purity is measured by HPLC (High-Performance Liquid Chromatography), and a Certificate of Analysis is available for every batch. Lyophilized material should be stored at -20°C or colder upon arrival.
LP1-S is supplied strictly for laboratory research use only and is not intended for human or animal use.
Our Process
Precision Lyophilization
Each batch is freeze-dried and sealed for stability until reconstitution.
Verified Purity
Every batch is third-party tested with HPLC and mass spectrometry.
Careful Fulfillment
Orders ship within 24 hours from our U.S. facility.